Mitochondrial Fission Dynamics: Steering the Future of Mitochondrial Quality Control and Regeneration

Mitochondrial Fission Dynamics: Steering the Future of Mitochondrial Quality Control and Regeneration

Tatjana Kleele, Institute of Biochemistry, ETH Zurich, Switzerland

Dr. Tatjana Kleele from the Institute of Biochemistry, ETH Zurich, Switzerland, will join the Targeting Mitochondria 2025 Congress and will give a presentation about Mitochondrial Fission Dynamics: Steering the Future of Mitochondrial Quality Control and Regeneration.

Dr. Kleele leads a pioneering research team dedicated to unraveling the fundamental interplay between mitochondrial structure, their dynamic behavior, and their crucial metabolic roles within the cell. Her group's work directly addresses the central question of how mitochondria interpret a multitude of cellular signals to precisely regulate the opposing processes of fission and fusion, thereby expertly tailoring their shape and organization to meet the cell's ever-evolving demands.

In her presentation, Dr. Kleele will share her groundbreaking discoveries that have reshaped the field, revealing that mitochondrial fission is not a random process, but a strategic decision point determining whether mitochondria undergo degradation or regeneration. Her insightful findings offer a compelling vision for how a deeper understanding and potential manipulation of these fission dynamics could revolutionize strategies for mitochondrial quality control, pave the way for innovative interventions in aging, and unlock new possibilities in regenerative medicine.

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