
Development of Mitochondria-Based Therapeutic Strategies for Disease Treatment
Summary
In recent years, the application of mitochondria isolated from cells for disease treatment has gained increasing attention, with their efficacy demonstrated in several diseases. However, the functions and characteristics of isolated mitochondria remain largely unknown, and their kinetics after administration into the body have yet to be fully elucidated.
In this presentation, Dr. Kosuke Kusamori will introduce a novel mitochondria-based therapeutic strategy using isolated mitochondria derived from mesenchymal stromal cells. This study investigates the physicochemical properties of mitochondria, their in vivo biodistribution, and their ability to restore cellular function in damaged tissues. Their findings underscore the potential of engineered mitochondria as a next-generation therapeutic modality for the treatment of intractable diseases.
About Dr. Kosuke Kusamori
Dr. Kosuke Kusamori is an Associate Professor at Tokyo University of Science. His research focuses on mitochondrial medicine, regenerative therapy, and cellular therapeutics. He has developed innovative approaches for mitochondrial transplantation and tissue regeneration, with a particular interest in therapeutic applications for liver failure and other intractable conditions.