Blood-Based Marker: Mitochondrial DNA Damage in Parkinson’s Disease

Laurie SandersDr. Laurie Sanders, Duke University School of Medicine, USA, will be joining Targeting Mitochondria 2024 this October in Berlin. 

Presentation title: Blood-Based Marker: Mitochondrial DNA Damage in Parkinson’s Disease

In this talk, Dr. Sanders will discuss the challenges in Parkinson's disease (PD) treatment and the need for better diagnostic tools. Mitochondrial dysfunction's role in PD's development will be highlighted, along with recent findings on mitochondrial DNA (mtDNA) damage. Dr. Sanders will introduce a PCR-based assay called MitoDNADX for quantifying mtDNA damage, showcasing its potential as a blood-based marker for PD. Preliminary results from patient studies and animal models will be presented, suggesting that this assay could aid in PD diagnosis and assessing the effectiveness of LRRK2 kinase inhibitors in treating the disease.

World Mitochondria Society 
Annual World Congress on Targeting Mitochondria
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